Ellen W. Demerath

Maternal diet and genetics shape the human milk metabolome

This study identifies how maternal diet and genetics influence the human milk metabolome, showing diet explains the most variation and uncovering genetic associations with specific metabolites.

Human milk variation is shaped by maternal genetics and impacts the infant gut microbiome

The paper identifies genetic loci influencing milk gene expression and links these to infant gut microbiome composition in breastfeeding mothers.

Human Cytomegalovirus in breast milk is associated with milk composition, the infant gut microbiome, and infant growth

The paper investigates the association between human cytomegalovirus in breast milk and milk composition, infant gut microbiome, and infant growth.

Understanding the genetic complexity of puberty timing across the allele frequency spectrum

This study identifies genetic signals associated with age at menarche, highlights genes involved in pubertal development, and links reproductive timing to later life disease risk.

Epigenome-wide meta-analysis of BMI in nine population-based cohorts: examining the utility of methylation as a biomarker of BMI

This study identifies CpG sites associated with BMI and shows that epigenetic BMI prediction correlates with metabolic health markers.

Methylome-Wide Association Study Of Central Adiposity Implicates Genes Involved In Immune And Endocrine Systems

This study identifies DNA methylation sites associated with central adiposity traits in adults and adolescents using methylome-wide association analyses across multiple cohorts.

PROTEIN-CODING VARIANTS IMPLICATE NOVEL GENES RELATED TO LIPID HOMEOSTASIS CONTRIBUTING TO BODY FAT DISTRIBUTION

This study identifies 15 common and 9 low-frequency protein-coding variants associated with body fat distribution, implicating novel genes related to lipid homeostasis and type 2 diabetes.