Author

Samuele Ambrosini

University of ZurichORCID 0000-0002-2112-1122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alessandro MengozziiD· 1 shared Era GoricaiD· 1 shared Francesco PaneniiD· 1 shared Frank Thomas RuschitzkaiD· 1 shared Gergely KarsaiiD· 1 shared Junyan XiaiD· 1 shared Kaivalya WalavalkariD· 1 shared Loek van HeerebeekiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Alessandro MengozziORCID

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1 paper

Recent·Most cited

PhysiologyCirculation ResearchPeer-reviewedApr 11, 2025

Chromatin Remodeling by the Histone Methyltransferase SETD2 Drives Lipotoxic Injury in Cardiometabolic Heart Failure with Preserved Ejection Fraction

Sarah Costantino, S. A. Mohammed, Samuele Ambrosini…·Francesco Paneni

This study shows that SETD2 promotes lipotoxic injury in cHFpEF by regulating SREBP1 and lipid metabolism, and its inhibition improves cardiac function.

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