Kaivalya Walavalkar

This study shows that excess cell size drives senescence by altering mRNA homeostasis and reorganizing the genome, leading to the secretory phenotype and cell cycle arrest.

This study identifies TCF3::HLF's role in rewiring the 3D genome to drive leukemia by regulating MEF2C and altering hematopoietic stem cell gene expression.

This paper introduces NoLMseq, a method to map nucleolar-associated domains (NADs) in single cells, revealing their heterogeneity and response to nucleolar stress.

This study shows that SETD2 promotes lipotoxic injury in cHFpEF by regulating SREBP1 and lipid metabolism, and its inhibition improves cardiac function.

This study examines how HPV integration affects host chromatin structure and gene regulation in cervical cancer, finding that integrations are enriched in active chromatin regions and induce local and long-range transcriptional upregulation within TADs.

The paper shows boundary-associated RNAs enhance TAD insulation by promoting CTCF clustering at TAD boundaries.

The paper evaluates image quality in scientific publications, identifying common issues and providing guidelines to improve clarity and accessibility.

The paper shows that unliganded ERα pre-marks enhancer sites, which form 3D clusters upon ligand exposure, driving transient gene expression.