Matrix stiffness shifts the endothelial shear stress set point for angiogenic activation
Laia Gifre-Renom, Ashkan Tabibian, Wolfgang Giese, Femke Bellen, Aernout Luttun, Hans Van Oosterwyck, Elizabeth A. V. Jones
This paper investigates how matrix stiffness and shear stress jointly influence endothelial gene expression and angiogenic activation thresholds using transcriptomics.
bioRxiv · Jul 23, 2026 · PreprintCell Biology