Author

Axel K.F. Aguettaz

Centre Hospitalier Universitaire VaudoisORCID 0000-0002-2116-9732Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Cassandra TabassoiD· 2 shared Francesca AmatiiD· 2 shared Sylviane LagarrigueiD· 2 shared Alexandra Schmitt· 1 shared Aminata Gerihanov· 1 shared Bryan C. BergmaniD· 1 shared Chaitanya K. GaviniiD· 1 shared Christel GenoudiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Cassandra TabassoORCID

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Author profile →

2 papers

Recent·Most cited

Alternative exon splicing reveals hidden mitochondrial targeting of PLIN3

Axel K.F. Aguettaz, Yoan Arribat, Alexandra Schmitt, Aminata Gerihanov, Jocelyn Fleurimont, Jean Daraspe, Vithusan Vijayatheva, Cassandra Tabasso, Sylviane Lagarrigue, Ernesto Picardi, Sarah Cohen, Christel Genoud, Francesca Amati

The paper identifies an alternative splicing event in PLIN3 that generates a mitochondrial-targeted transcript, PLIN3B, which is unstable and not detectable as endogenous protein.

bioRxiv · Feb 19, 2026 · PreprintCell Biology

Organelle-specific lipid profiles influence/underlie metabolic health in a nutrition-dependent manner

Cassandra Tabasso, Chaitanya K. Gavini, Karin A. Zemski Berry, Hadi Salem, Axel K.F. Aguettaz, Sylviane Lagarrigue, Bryan C. Bergman, Virginie Mansuy‐Aubert, Francesca Amati

This study shows that dietary fat affects mitochondrial and lipid droplet lipid profiles in skeletal muscle, with specific lipid classes linked to metabolic health and insulin resistance.

bioRxiv · Dec 26, 2025 · PreprintPhysiology