Jean Daraspe

This paper uses cryo-ET to study amyloid fibrils in neurodegenerative brain tissue, revealing ultrastructural details of fibril polymorphs and their association with disease.

The paper identifies atonosomes as tension-responsive plasma membrane-derived compartments in yeast, showing they form rapidly in response to membrane tension loss and are regulated by cell wall dynamics.

The paper identifies an alternative splicing event in PLIN3 that generates a mitochondrial-targeted transcript, PLIN3B, which is unstable and not detectable as endogenous protein.

This study identifies C2CD3 as a radial organizer of the distal centriole and appendages, revealing its role in structuring the luminal ring and interacting with the DISCO complex.

This study uses cryo-electron tomography to compare replication structures of African and Asian Zika virus lineages, revealing lineage-specific ultrastructural features linked to congenital disease potential.

The paper improves cryo-CLEM and cryo-ET techniques for imaging plant cell walls with enhanced precision and reduced contamination, enabling detailed structural analysis of root-specific features.

This paper provides a protocol for correlative light and electron microscopy (CLEM) optimized for analyzing human brain tissue, enabling detailed ultrastructural analysis and characterization of subcellular features.