Elena Blanco‐Suárez

Astrocytic chordin-like 1 (Chrdl1) is re-engaged early after ischemic stroke to regulate region-dependent GluA2 levels and neuronal vulnerability

This study identifies Chrdl1's role in regulating neuronal vulnerability after ischemic stroke by stabilizing GluA2 and limiting apoptosis, with region-dependent effects.

Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires handling associated with repeated behavioral testing.

This study shows that handling with behavioral testing is necessary for EVs to improve recovery in post-stroke rats, and a single EV dose enhances this recovery without affecting ischemic damage.

Astrocyte-secreted chordin-like 1 regulates spine density after ischemic stroke

This study investigates the role of Chrdl1 in regulating spine density and recovery after ischemic stroke using Chrdl1 knockout mice.

Activity-Dependent Modulation of Synapse-Regulating Genes in Astrocytes

The paper identifies astrocyte synapse-regulating genes in the developing mouse visual cortex and shows their expression is modulated by neuronal activity and calcium signaling.