Author

Kazumasa Aoyama

Keio UniversityORCID 0000-0002-2136-4562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Yangsu Cho· 2 shared Atsushi IwamaiD· 1 shared Hidetaka KosakoiD· 1 shared Kosuke Higashi· 1 shared Makiko Miyota-Yui· 1 shared Motohiko Oshima· 1 shared Ryo Uchidaya· 1 shared So Taguchi· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMolecular Biology

Yangsu Cho

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Author profile →

3 papers

Recent·Most cited

Coffee induces chromatin structural changes associated with histone H4K16 hypoacetylation

Yasuko Tanaka, Yangsu Cho, Yuusuke Suwabe, Sora Misaki, Ryo Uchidaya, Kazumasa Aoyama

This study shows coffee reduces H4K16ac levels and alters chromatin structure, with transcriptional changes in K562 cells.

bioRxiv · Oct 20, 2026 · PreprintMolecular Biology

Coffee remodels the global histone acetylation landscape with reduced H3K27ac at the MYC promoter

Yangsu Cho, Makiko Miyota-Yui, Yaeko Nakajima‐Takagi, Takako Yokomizo, Motohiko Oshima, Atsushi Iwama, Kazumasa Aoyama

This study shows coffee reduces histone acetylation, particularly H3K27ac at the MYC promoter, leading to suppression of the MYC transcriptional program and inhibition of cancer cell proliferation.

bioRxiv · Aug 3, 2026 · PreprintMolecular Biology

Oncogenic NPM-ALK reprograms the TGM1 1 interactome toward oncogenic signaling and transcriptional states

So Taguchi, Kosuke Higashi, Yuuki Tanaka, Hidetaka Kosako, Kazumasa Aoyama

This study identifies how NPM-ALK alters the TGM1 interactome to support oncogenic signaling and proliferation.

bioRxiv · Aug 3, 2026 · PreprintMolecular Biology