Author

Yaeko Nakajima‐Takagi

Institute of Medical Science, The University of TokyoORCID 0000-0002-2341-2409Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Atsushi IwamaiD· 2 shared Akira SuzukiiD· 1 shared Atsushi KanedaiD· 1 shared Ayako Aihara· 1 shared Bahityar RahmutullaiD· 1 shared Kazumasa AoyamaiD· 1 shared Kenta Kagaya· 1 shared Makiko Miyota-Yui· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Atsushi IwamaORCID

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2 papers

Recent·Most cited

Coffee remodels the global histone acetylation landscape with reduced H3K27ac at the MYC promoter

Yangsu Cho, Makiko Miyota-Yui, Yaeko Nakajima‐Takagi, Takako Yokomizo, Motohiko Oshima, Atsushi Iwama, Kazumasa Aoyama

This study shows coffee reduces histone acetylation, particularly H3K27ac at the MYC promoter, leading to suppression of the MYC transcriptional program and inhibition of cancer cell proliferation.

bioRxiv · Aug 3, 2026 · PreprintMolecular Biology

Niche-targeted therapy via YAP/TAZ activation enhances hematopoietic regeneration

Shun Uemura, Masayuki Yamashita, Takako Yokomizo‐Nakano, Ayako Aihara, Takumi Iwawaki, Shuhei Koide, Yaeko Nakajima‐Takagi, Motohiko Oshima, Yoshiki Omatsu, Yuki Matsumoto, Yoshiaki Kubota, Bahityar Rahmutulla, Atsushi Kaneda, Miki Nishio, Akira Suzuki, , Atsushi Iwama

This study shows that activating YAP/TAZ improves bone marrow niche recovery and hematopoietic regeneration after myeloablative stress.

Blood · Jun 22, 2026Peer-reviewedCell Biology