Author

Muhammad Nauman Arshad

Tufts UniversityORCID 0000-0002-2144-9718Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:proteomics· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Joshua L. SmalleyiD· 2 shared Paul A DaviesiD· 2 shared Stephen J. MossiD· 2 shared Toshiya NishiiD· 2 shared Zhong Zhong· 2 shared Bilge Büyükdemirtaş· 1 shared Christopher E. Bope· 1 shared Jacob S. Dengler· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Joshua L. SmalleyORCID

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3 papers

Recent·Most cited

KCC2 Activation Reverses Neurophysiological and Behavioral Deficits in Female Rett Mice

Muhammad Nauman Arshad, Josephine Ng, Seda Salar, Krithika Abiraman, Toshiya Nishi, Zhong Zhong, Joshua L. Smalley, Paul A Davies, Stephen J. Moss

This study shows that activating KCC2 improves neurophysiological and behavioral symptoms in female Rett syndrome mice.

bioRxiv · Jan 14, 2026 · PreprintNeuroscience

Activation of KCC2 during development alleviates cognitive, behavioral, and neural excitability in adult CDKL5-deficient mice

Muhammad Nauman Arshad, Christopher E. Bope, Jacob S. Dengler, Shu Fun Josephine Ng, Joshua L. Smalley, Toshiya Nishi, Zhong Zhong, Stephen J. Moss, Paul A Davies

This study shows that activating KCC2 during development reduces seizures, cognitive, and behavioral issues in adult CDKL5-deficient mice, but adult treatment is less effective.

bioRxiv · Feb 26, 2025 · PreprintNeuroscience

Hippocampal Transplants of Fetal GABAergic Progenitors Regulate Adult Neurogenesis in Mice with Temporal Lobe Epilepsy

Muhammad Nauman Arshad, Simon Oppenheimer, Jaye Jeong, Bilge Büyükdemirtaş, Janice R. Naegele

This study shows that transplanting fetal GABAergic progenitors into mice with temporal lobe epilepsy reduces seizure frequency by correcting abnormalities in adult neurogenesis.

Neurobiology of Disease · Sep 29, 2022Peer-reviewedNeuroscience