Author

Scot R. Kimball

Penn State Cancer InstituteORCID 0000-0002-2149-7189Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashley Elizabeth ShayiD· 1 shared Bin QiaoiD· 1 shared Bo Ni· 1 shared Boyang Fu· 1 shared Chenyang Meng· 1 shared Dongxiao SuniD· 1 shared Girish Halemirle RajacharyaiD· 1 shared Guangcong SheniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Ashley Elizabeth ShayORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma

Yunzhan Li, Zekun Li, Qin Li, Dongxiao Sun, Bo Ni, Mingjun Tan, Ashley Elizabeth Shay, M. Wang, Chenyang Meng, Guangcong Shen, Boyang Fu, Yu Shan, Shiqi Zhang, Rifah Rownak Tanshee, Tianxing Zhou, , Shengyu Yang

This study shows that adaptation to cystine limitation stress in PDAC promotes tumor growth via lipid metabolism reprogramming, and lomitapide can inhibit this process and enhance chemotherapy.

Nature Communications · Dec 31, 2025Peer-reviewedCancer Biology