Author

Dongxiao Sun

Pennsylvania State UniversityORCID 0000-0003-4902-4292Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:rat· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Ashley Elizabeth ShayiD· 1 shared Bin QiaoiD· 1 shared Bo Ni· 1 shared Boyang Fu· 1 shared Brooke Stoltzfus· 1 shared Chenyang Meng· 1 shared Elizabeth M. NeslundiD· 1 shared Girish Halemirle RajacharyaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperCancer Biology

Ashley Elizabeth ShayORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma

Yunzhan Li, Zekun Li, Qin Li, Dongxiao Sun, Bo Ni, Mingjun Tan, Ashley Elizabeth Shay, M. Wang, Chenyang Meng, Guangcong Shen, Boyang Fu, Yu Shan, Shiqi Zhang, Rifah Rownak Tanshee, Tianxing Zhou, , Shengyu Yang

This study shows that adaptation to cystine limitation stress in PDAC promotes tumor growth via lipid metabolism reprogramming, and lomitapide can inhibit this process and enhance chemotherapy.

Nature Communications · Dec 31, 2025Peer-reviewedCancer Biology

Methoxsalen inhibited the acquisition of nicotine self-administration: attenuation by cotinine replacement in rats

Zheng‐Ming Ding, Elizabeth M. Neslund, Dongxiao Sun, Xiaoying Tan

The paper investigates how methoxsalen inhibits nicotine self-administration in rats and shows that cotinine replacement can counteract this effect.

bioRxiv · Jun 4, 2023 · PreprintNeuroscience

Acute Glucagon-Like Peptide-1 Receptor Agonist Liraglutide Prevents Drug-Induced Heroin Seeking in Rats

Joaquin E. Douton, Nikhil Acharya, Brooke Stoltzfus, Dongxiao Sun, Patricia S. Grigson, Jennifer E. Nyland

This study shows that liraglutide, a GLP-1 receptor agonist, prevents heroin seeking in rats when administered with an appropriate pretreatment time, without affecting locomotion.

bioRxiv · Sep 15, 2021 · PreprintNeuroscience