Author

Shiqi Zhang

Oslo University HospitalORCID 0000-0001-9751-7652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Ashley Elizabeth ShayiD· 1 shared Beatriz Escobar-DonceliD· 1 shared Bin QiaoiD· 1 shared Bo Ni· 1 shared Boyang Fu· 1 shared Chenglong XieiD· 1 shared Chenyang Meng· 1 shared Dongxiao SuniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Ashley Elizabeth ShayORCID

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2 papers

Recent·Most cited

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma

Yunzhan Li, Zekun Li, Qin Li, Dongxiao Sun, Bo Ni, Mingjun Tan, Ashley Elizabeth Shay, M. Wang, Chenyang Meng, Guangcong Shen, Boyang Fu, Yu Shan, Shiqi Zhang, Rifah Rownak Tanshee, Tianxing Zhou, , Shengyu Yang

This study shows that adaptation to cystine limitation stress in PDAC promotes tumor growth via lipid metabolism reprogramming, and lomitapide can inhibit this process and enhance chemotherapy.

Nature Communications · Dec 31, 2025Peer-reviewedCancer Biology

NAD+ - and EVA1-C-dependent reversal of neurological deficits is mediated by differential alternative RNA splicing in tauopathic animal models

Ruixue Ai, Lipeng Mao, Xurui Jin, Shiqi Zhang, Junping Pan, Mariá José Lagartos-Donate, Shuqin Cao, Guang Yang, Chenglong Xie, Xiongbin Kang, Pingjie Wang, Yang Hu, Linda Hildegard Bergersen, Jon Storm‐Mathisen, Hidehito Kuroyanagi, , Evandro Fei Fang

The paper shows NAD+ and EVA1-C regulate alternative splicing in tauopathies, affecting protein interactions and disease progression, suggesting therapeutic potential for AD.

bioRxiv · Oct 27, 2024 · PreprintNeuroscience