Author

Mingjun Tan

Penn State Cancer InstituteORCID 0000-0003-2210-6319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Alec T. McIntoshiD· 1 shared Anna Kasprzyk-Pawelec· 1 shared Ashley Elizabeth ShayiD· 1 shared Bin QiaoiD· 1 shared Bo Ni· 1 shared Boyang Fu· 1 shared Chenyang Meng· 1 shared Christopher AlbaneseiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Alec T. McIntoshORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedDec 31, 2025

Adaptation to cystine limitation stress confers a targetable lipid metabolism vulnerability in pancreatic ductal adenocarcinoma

Yunzhan Li, Zekun Li, Qin Li…·Shengyu Yang

This study shows that adaptation to cystine limitation stress in PDAC promotes tumor growth via lipid metabolism reprogramming, and lomitapide can inhibit this process and enhance chemotherapy.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 18, 2023

Loss of the mitochondrial carrier, SLC25A1, during embryogenesis induces a unique senescence program controlled by p53

Anna Kasprzyk-Pawelec, Mingjun Tan, Raneen Rahhal…·Maria Laura Avantaggiati

This study shows that SLC25A1 deficiency in mice causes senescence via p53-dependent pathways, leading to developmental disorders similar to human D/L-2HGA.

5 citations

mousestatistical model

𝕏 PostBluesky