Author

Paturu Kondaiah

Indian Institute of Science BangaloreORCID 0000-0002-2159-1044Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Anahita Jayaram· 1 shared Annapoorni RangarajaniD· 1 shared Arka Baksi· 1 shared Armin GandhiiD· 1 shared Dharma PallyiD· 1 shared Divya BeriiD· 1 shared Namrata GundiahiD· 1 shared Neha PaddillayaiD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBioengineering

Anahita Jayaram

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Stromal LOX/FAK/beta catenin pathway locks mammary fibroblasts into a tumor-promoting myCAF state

Armin Gandhi, Divya Beri, Dharma Pally, Sathish Manjunath, Sharadhi Humcha, Annapoorni Rangarajan, Rekha V. Kumar, Ramray Bhat, Utpal Shashikant Tatu, Paturu Kondaiah

This study identifies LOX as a key mediator of TGF-β-induced myCAF state in breast cancer, showing its role in promoting tumor growth through a LOX/FAK/GSK3β/β-catenin pathway.

bioRxiv · Jul 11, 2025 · PreprintCancer Biology

Mechanotransduction and Biophysical Regulation of Fibroblast Plasticity Under Prolonged Shear Stress

Neha Paddillaya, Anahita Jayaram, Paturu Kondaiah, Namrata Gundiah

This study shows prolonged shear stress induces fibroblast-to-myofibroblast transition through mechanical and biochemical changes, with lasting effects on cell morphology, adhesion, and migration.

bioRxiv · Mar 3, 2025 · PreprintBioengineering

Correlation between the aberrant human testicular germ-cell gene expression and disruption of spermatogenesis leading to male infertility

Arka Baksi, Ruchi Jain, Ravi R. Manjithaya, SS Vasan, Paturu Kondaiah, Rajan R. Dighe

This study identifies gene expression patterns in testicular germ cells from azoospermia patients and links disruptions to spermatogenic arrest and male infertility.

bioRxiv · Aug 17, 2018 · PreprintGenomics