Ramray Bhat

This study shows tannic acid protects extracellular matrix from methylglyoxal-induced damage by stabilizing its biochemical properties and restoring cell adhesion.

This study shows dicarbonyl stress weakens mesothelial barriers, enabling ovarian cancer metastasis, and identifies GLO-1 as a potential therapeutic target.

This study evaluates fractal measures for distinguishing malignant from normal breast mammograms and assessing molecular subtype differentiation, finding moderate discriminatory performance.

This study develops a cell-based model of intermittent attachments to explain how cell aggregates exhibit fluid-like properties and collective chemotaxis.

This study shows that cancer-associated fibroblasts enhance breast cancer cell migration via laminin-511-induced cortical Arp2/3 localization.

This study identifies LOX as a key mediator of TGF-β-induced myCAF state in breast cancer, showing its role in promoting tumor growth through a LOX/FAK/GSK3β/β-catenin pathway.

This study shows that PKM2 and YAP reciprocally regulate metabolic and migratory states in breast cancer cells based on matrix stiffness.

This study examines how three dicarbonyls affect extracellular matrix interactions with human cells, revealing distinct impacts on matrix structure and cellular behavior.

The paper uses a multiscale model to show that mesenchymally transitioned tumor niches outcompete parental niches under specific adhesion and ECM conditions.

This study shows dicarbonyl stress increases cancer cell intravasation by degrading ECM and promoting endothelial dysfunction in a microfluidic model.

This study quantifies how ovarian cancer cells adapt their migration strategies on different stiffness collagen substrates, revealing distinct behaviors between epithelioid and mesenchymal cell lines.

This study shows drug-resistant ovarian cancer cells exhibit collective amoeboid dynamics that enhance their ability to colonize and invade tissues.

This paper uses a computational model to show how spatial heterogeneity in cell adhesion affects collective cell migration in tumors.

The paper identifies metabolic reaction modules driving metastatic transitions in ovarian cancer and validates oseltamivir as a non-cytotoxic drug to disrupt spheroidal morphologies.

The paper identifies ancient matrisomal glycoprotein genes frequently mutated across cancers, showing their role in tissue morphogenesis and neoplastic transformation.

This study shows that prolactin-induced AMPK regulates mammary alveologenesis and lactogenesis by modulating STAT5 signaling in mice.

The paper shows that precartilage condensation in limb development occurs via a bistable cell-state switch driven by galectins, without oscillatory dynamics.

The paper analyzes N-linked glycosylation sites in human glycoproteins and finds they are more prevalent in ordered regions than disordered regions, suggesting a functional trade-off between protein stability and flexibility.