Michael E. Baumgartner

Interclonal cooperation and suppression shape early Ras-driven tumour growth

This study identifies cooperative and suppressive interclonal interactions during early Ras-driven tumourigenesis using a Drosophila model, revealing key modifiers like SWI/SNF and cell competition regulators.

Xrp1 and Irbp18 trigger a feed-forward loop of proteotoxic stress to induce the loser status

The paper shows that Xrp1 and Irbp18 create a feed-forward loop of proteotoxic stress that causes cells to become losers in competition.

Ribosome protein mutant cells rely on the GR64 cluster of gustatory receptors for survival and proteostasis in Drosophila

The paper shows that Rp/+ cells in Drosophila rely on Gr64 gustatory receptors for survival and proteostasis by maintaining autophagy and proteasome function.