Colin P McNally

The paper introduces IDLI, a method to map nucleosome structures and distortion patterns in mammalian chromatin, revealing widespread and regulated DNA accessibility across cell types.

This study introduces RASAM, a method to analyze nascent chromatin structure, finding that newly replicated chromatin is hyperaccessible and has unique organization features.

The paper trains bidirectional transformer models to predict RNA splicing using perturbative RNA data, achieving state-of-the-art performance in splice junction prediction.

This study uses a single-molecule platform to show that SNF2h, a chromatin remodeler, regulates DNA accessibility based on nucleosome density in vitro and in vivo.

The paper introduces a single-molecule sequencing method to measure nucleosome positions on chromatin fibers and reveals heterogeneous patterns of oligonucleosome occupancy across epigenomic domains.

BURRITO is a web tool that visualizes microbiome multi-omic data, linking taxonomic and functional compositions to explore their co-variation.