Marty G. Yang

This study shows that FACT is essential for chromatin replication and transcription by disrupting and reassembling nucleosomes, preventing genome aggregation.

The paper develops a mouse cortical organoid platform to study cis-regulatory evolution and identifies genes with dynamic allelic imbalances during neurogenesis.

The paper introduces IDLI, a method to map nucleosome structures and distortion patterns in mammalian chromatin, revealing widespread and regulated DNA accessibility across cell types.

This study introduces RASAM, a method to analyze nascent chromatin structure, finding that newly replicated chromatin is hyperaccessible and has unique organization features.

The paper identifies sequence variants affecting enhancer function by analyzing TF binding and activity in hybrid mice fibroblasts.

The paper identifies cis-regulatory elements and their genetic variation in human retina, macula, and RPE using epigenomic profiling and single-nucleus RNA-seq.