Author

Wei Zhou

GenentechORCID 0000-0002-2175-726XUnclaimed ORCID profile · follow to get notified of new preprints

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Wei Zhou11 papers · Duke University

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ciara MetcalfeiD· 2 shared Marc A. HafneriD· 2 shared Aaron T. L. LuniD· 1 shared Adrian Waddell· 1 shared Alejandro Martinez ChiblyiD· 1 shared Aleksander ChlebowskiiD· 1 shared Antonina HafneriD· 1 shared Bence DánieliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Ciara MetcalfeORCID

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2 papers

Recent·Most cited

Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state

Tomasz Włodarczyk, Aaron T. L. Lun, Diana H. Wu, Minyi Shi, Xiaofen Ye, Shreya Menon, Shushan Toneyan, Kerstin Seidel, Liang Wang, Jenille Tan, Shang-Yang Chen, Timothy Keyes, Aleksander Chlebowski, Adrian Waddell, Wei Zhou, , Xiaosai Yao

Epiregulon infers single-cell TF activity using ATAC-seq and RNA-seq to predict drug response and identify drivers of cell state.

Nature Communications · Aug 2, 2025Peer-reviewedBioinformatics

Transformer-based modeling of Clonal Selection and Expression Dynamics (TraCSED) reveals resistance signatures in breast cancer

Nathan D Maulding, Jun Zou, Wei Zhou, Ciara Metcalfe, Joshua M. Stuart, Xin Ye, Marc A. Hafner

TraCSED identifies resistance pathways in breast cancer by analyzing scRNA-seq data and clonal selection dynamics over time.

npj Systems Biology and Applications · Jan 10, 2025Peer-reviewedCancer Biology