Author

Aleksander Chlebowski

Institute of Biochemistry and Biophysics, Polish Academy of SciencesORCID 0000-0001-5018-6294Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Andrzej DziembowskiiD· 3 shared Dominik CysewskiiD· 2 shared Ewelina P. OwczarekiD· 2 shared Kamila AffekiD· 2 shared Kamila Kłosowska-KosickaiD· 2 shared Paweł Szczepan KrawczykiD· 2 shared Roman J. SzczęsnyiD· 2 shared Aaron T. L. LuniD· 1 shared

Activity by Year

2018-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersSystems Biology

Andrzej DziembowskiORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BioinformaticsNature CommunicationsPeer-reviewedAug 2, 2025

Epiregulon: Inference of single-cell transcription factor activity to predict drug response and drivers of cell state

Tomasz Włodarczyk, Aaron T. L. Lun, Diana H. Wu…·Xiaosai Yao

Epiregulon infers single-cell TF activity using ATAC-seq and RNA-seq to predict drug response and identify drivers of cell state.

13 citations

humanscATAC-seq

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Systems BiologybioRxivPreprintAug 5, 2020

High-throughput siRNA screening reveals functional interactions and redundancies of human processive exoribonucleases

Anna Hojka-Osińska, Aleksander Chlebowski, Ewelina P. Owczarek…·Andrzej Dziembowski

The paper uses high-throughput siRNA screening to identify functional interactions and redundancies among human processive exoribonucleases in RNA metabolism.

DOI 10.1101/2020.08.05.238006

humanexperimental assay

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GeneticsCell ReportsPeer-reviewedJan 1, 2020

Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

Olga Gewartowska, Goretti Aranaz Novaliches, Paweł Szczepan Krawczyk…·Andrzej Dziembowski

This study identifies TENT5A as a cytoplasmic poly(A) polymerase essential for collagen production and bone formation, revealing its role in osteogenesis imperfecta type XVIII.

60 citations

mousebulk RNA-seq

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Molecular BiologyPLoS ONEPeer-reviewedMar 28, 2018

Versatile approach for functional analysis of human proteins and efficient stable cell line generation using FLP-mediated recombination system

Roman J. Szczęsny, Katarzyna Julia Kowalska, Kamila Kłosowska-Kosicka…·Andrzej Dziembowski

The paper develops a versatile vector system for protein functional analysis and stable cell line generation using FLP-mediated recombination, validated with multiple protein tags and applications.

64 citations

humanproteomics

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