Author

Gheorghița Isvoranu

ORCID 0000-0002-2185-019XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Andreas BenderiD· 1 shared Cristian PopiD· 1 shared Cristian V. A. MunteanuiD· 1 shared Gabriela N. ChirițoiuiD· 1 shared Julien VilleneuveiD· 1 shared Marioara Chiritoiu‐ButnaruiD· 1 shared Simona GheneaiD· 1 shared Stefana Maria PetrescuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperImmunology

Andreas BenderORCID

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1 paper

Recent·Most cited

A novel IL-1β reporter assay identifies tolcapone as a caspase-1 suppressor targeting pyroptosis in endotoxemia

Gabriela N. Chirițoiu, Simona Ghenea, Gheorghița Isvoranu, Julien Villeneuve, Cristian V. A. Munteanu, Cristian Pop, Andreas Bender, Stefana Maria Petrescu, Marioara Chiritoiu‐Butnaru

The paper develops a CRISPR-based IL-1β reporter assay to identify tolcapone as a caspase-1 inhibitor that suppresses pyroptosis in endotoxemia.

bioRxiv · Jul 21, 2026 · PreprintImmunology