Author

James Robinson

Broad InstituteORCID 0000-0002-2187-5944Unclaimed ORCID profile · follow to get notified of new preprints

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James Robinson1 paper

Biology Disciplines

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Bioinformatics· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1

Frequent Co-Authors

Douglass Turner· 2 shared Erez Lieberman AideniD· 2 shared Adrian L. SanborniD· 1 shared Alexander DobiniD· 1 shared Anne Van ArsdaleiD· 1 shared Arina D. OmeriD· 1 shared Aviv RegeviD· 1 shared B BernsteiniD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBioinformatics

Douglass Turner

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3 papers

Recent·Most cited

Targeted in silico characterization of fusion transcripts in tumor and normal tissues via FusionInspector

Brian J. Haas, Alexander Dobin, Mahmoud Ghandi, Anne Van Arsdale, Timothy L. Tickle, James Robinson, Riaz Gillani, Simon Kasif, Aviv Regev

FusionInspector identifies and characterizes biologically relevant fusion transcripts from RNA-seq data in tumor and normal tissues using clustering and machine learning.

Cell Reports Methods · May 1, 2023Peer-reviewedBioinformatics

Juicebox.js provides a cloud-based visualization system for Hi-C data

James Robinson, Douglass Turner, Neva C. Durand, Helga Thorvaldsdóttir, Jill P. Mesirov, Erez Lieberman Aiden

Juicebox.js is a cloud-based tool for visualizing Hi-C data, enabling users to explore and share 3D genome structures through an intuitive interface.

Cell Systems · Feb 1, 2018Peer-reviewedBioinformatics

Cohesin Loss Eliminates All Loop Domains, Leading To Links Among Superenhancers And Downregulation Of Nearby Genes

Suhas S.P. Rao, Su-Chen Eileen Huang, Brian Glenn St Hilaire, J Engreitz, Elizabeth M. Perez, Kyong-Rim Kieffer-Kwon, Adrian L. Sanborn, Sarah E. Johnstone, Gavin D. Bascom, Ivan D. Bochkov, Xingfan Huang, Muhammad S. Shamim, Jaeweon Shin, Douglass Turner, Ziyi Ye, , Erez Lieberman Aiden

This study shows that cohesin loss eliminates loop domains, causing superenhancer links and gene downregulation, which are reversible upon cohesin restoration.

Cell · Oct 1, 2017Peer-reviewedGenomics