Juicebox.js provides a cloud-based visualization system for Hi-C data

James Robinson; Douglass Turner; Neva C. Durand; Helga Thorvaldsdóttir; Jill P. Mesirov; Erez Lieberman Aiden

doi:10.1016/j.cels.2018.01.001

BioinformaticsCell SystemsFeb 1, 2018

Peer-reviewed journal article

Juicebox.js provides a cloud-based visualization system for Hi-C data

James Robinson iD, Douglass Turner, Neva C. Durand iD, Helga Thorvaldsdóttir, Jill P. Mesirov iD, Erez Lieberman Aiden iD

Abstract

Contact mapping experiments such as Hi-C explore how genomes fold in 3D. Here, we introduce Juicebox.js, a cloud-based web application for exploring the resulting datasets. Like the original Juicebox application, Juicebox.js allows users to zoom in and out of such datasets using an interface similar to Google Earth. Furthermore, Juicebox.js encodes the exact state of the browser in a shareable URL. Creating a public browser for a new Hi-C dataset does not require coding and can be accomplished in under a minute.

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