Author

Vrushank Dharmesh Bhatt

Rutgers Cancer InstituteORCID 0000-0002-2190-2164Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Akshada SawantiD· 2 shared Eileen WhiteiD· 2 shared Jessie Yanxiang GuoiD· 2 shared Amar MahdiiD· 1 shared Bing XiaiD· 1 shared Chang S. ChaniD· 1 shared Cheryl F. DreyfusiD· 1 shared Christian S. HinrichsiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

Akshada SawantORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RESPIRATION DEFECTS LIMIT SERINE SYNTHESIS REQUIRED FOR LUNG CANCER GROWTH AND SURVIVAL

Eduardo Cararo Lopes, Fuqian Shi, Akshada Sawant, Maria Ibrahim, Maria Gomez-Jenkins, Zhixian Hu, Pranav Manchiraju, Vrushank Dharmesh Bhatt, Wenping Wang, Christian S. Hinrichs, Douglas C. Wallace, Xiaoyang Su, Joshua D. Rabinowitz, Chang S. Chan, Jessie Yanxiang Guo, , Eileen White

This study shows that mitochondrial DNA mutations in NSCLC cause respiration defects, leading to glucose dependency, reduced serine synthesis, and increased cancer survival.

Nature Communications · Aug 15, 2025Peer-reviewedCancer Biology

PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7 to suppress p53 dependent neurodegeneration

Yanying Huo, Akshada Sawant, Yongmei Tan, Amar Mahdi, Tao Li, Hui Ma, Vrushank Dharmesh Bhatt, Run Yan, Jake Coleman, Cheryl F. Dreyfus, Jessie Yanxiang Guo, M. Maral Mouradian, Eileen White, Bing Xia

This study shows that PALB2 maintains redox and mitochondrial homeostasis in the brain and works with ATG7 to prevent p53-dependent neurodegeneration.

bioRxiv · Jun 7, 2021 · PreprintNeuroscience