Macrophage ferroptosis inhibits Aspergillus conidial killing in lung transplantation
Efthymia Iliana Matthaiou, Amer Ali Abd El‐Hafeez, Husham Sharifi, Paulami Chatterjee, Matt S. Zinter, Patrik K. Johansson, Ekroop Dhillon, Wayland Chiu, Jin Qian, Brian D. Shaller, Jiwoon Chang, Shravani Pasupneti, Carlos Hernandez Borges, Sarah Omar, Annika M. K. Enejder, , Joe L. Hsu
This study shows that macrophage ferroptosis impairs Aspergillus killing in lung transplant recipients, increasing fungal infection risk.
bioRxiv · Mar 13, 2025 · PreprintImmunology