Wim Derave

Deconvoluting fiber type proportions from human skeletal muscle transcriptomics and proteomics data using FibeRtypeR

This paper introduces FibeRtypeR, a tool to estimate muscle fiber type proportions from bulk transcriptomics and proteomics data using single-fiber reference profiles.

Big Bones Mean Big Muscles: AI Quantifies 71 Individual Muscles Across the Whole Body, Revealing Widespread Links Between Muscle, Bone, and Body Size

This study uses AI to analyze whole-body MRI scans, quantifying 71 muscles and 13 bones in healthy adults, revealing that skeletal size is a key determinant of muscularity.

Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis

This study shows that carnosine synthase deficiency worsens neuroinflammation in MS models but not demyelination, suggesting a role in neuroinflammation regulation.