Author
Hasselt UniversityORCID 0000-0003-2308-406XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Mirre De Bondt, Janne Renders, Yana Sterckx…·Sofie Struyf
The paper shows human neutrophils internalize myelin debris via complement receptor 3, leading to a pro-inflammatory phenotype in MS.
Melissa Schepers, Sven Hendrix, Femke Mussen…·Tim Vanmierlo
This study evaluates the effects of PDE4D inhibition on spinal cord injury outcomes, showing improved functional and histopathological results compared to PDE4B inhibition.
Jan Spaas, Thibaux Van der Stede, Sarah de Jager…·Wim Derave
This study shows that carnosine synthase deficiency worsens neuroinflammation in MS models but not demyelination, suggesting a role in neuroinflammation regulation.
Assia Tiane, Melissa Schepers, Rick A. Reijnders…·Tim Vanmierlo
The paper investigates DNA methylation and transcriptomic changes in chronic demyelinated MS lesions, showing hypermethylation of myelination-related genes and demonstrating reversible effects through epigenetic editing.