Author

Clara Serger

University of BaselORCID 0000-0002-2236-7300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Alfred ZippeliusiD· 2 shared Andreas ZinggiD· 2 shared Mascha BinderiD· 2 shared Michael T. SandholzeriD· 2 shared Sarp UzuniD· 2 shared Alessia G LineriD· 1 shared Aljaž HojskiiD· 1 shared Andrea Romagnani· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Alfred ZippeliusORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Longitudinal profiling of tumor-reactive T cells during TIL therapy in metastatic melanoma

Michael T. Sandholzer, Clara Serger, Alessia G Liner, Sarp Uzun, David König, Helen Thut, Reto Ritschard, Jonas D. Fürst, Andreas Zingg, Natália Rodrigues Mantuano, Benjamin Kasenda, Katharina Glatz, Elisabeth A. Kappos, Matthias Sebastian Matter, Andreas Holbro, , Heinz Philipp Laubli

This study profiles tumor-reactive T cell dynamics during TIL therapy in metastatic melanoma, identifying factors associated with response and resistance.

bioRxiv · Sep 23, 2025 · PreprintImmunology

CD39 defines a cytotoxic tumor-associated NK cell state responsive to NKG2A blockade in lung cancer

Clara Serger, Lucas Rebuffet, Michael T. Sandholzer, Wiebke Rackwitz, Irene Fusi, Petra Herzig, Annalea Brüggemann, Carina A. Pawlow, Evgeny Chichelnitskiy, Daniel Hajnal, Nicole Oelgarth, Sarp Uzun, Christoph Schultheiß, Andreas Zingg, Sofia Tundo, , Alfred Zippelius

The paper identifies CD39+ tumor-associated NK cells as a cytotoxic effector state in NSCLC responsive to NKG2A blockade through multiomic analysis.

bioRxiv · Aug 26, 2025 · PreprintImmunology

Single-cell transcriptomics reveals immune response of intestinal cell types to viral infection

Sergio Triana, Megan Lynn Stanifer, Camila Metz‐Zumaran, Mohammed Shahraz, Markus Mukenhirn, Carmon Kee, Clara Serger, Ronald Koschny, Diana Ordoñez‐Rueda, Malte S. Paulsen, Vladimı́r Beneš, Steeve Boulant, Theodore Alexandrov

The paper uses single-cell RNA-Seq and imaging to study how intestinal cell types respond to viral infection, finding that each lineage has unique antiviral responses.

Molecular Systems Biology · Jul 1, 2021Peer-reviewedSystems Biology