Author
University of BaselORCID 0009-0005-4842-6013Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Johanna Nimmerfroh, Dinah Heiligensetzer, Michael T. Sandholzer…·Heinz Philipp Laubli
Desialylation enhances bispecific T cell engager responses by relieving a sialoglycan-dependent restraint in human T cells.
Natália Rodrigues Mantuano, Michael T. Sandholzer, Emiel Rossing…·Heinz Philipp Laubli
This study shows that local glycan engineering using AAV-delivered sialidases reduces tumor growth and enhances systemic antitumor immunity through improved cross-presentation and dendritic cell activation.
Michael T. Sandholzer, Clara Serger, Alessia G Liner…·Heinz Philipp Laubli
This study profiles tumor-reactive T cell dynamics during TIL therapy in metastatic melanoma, identifying factors associated with response and resistance.
Clara Serger, Lucas Rebuffet, Michael T. Sandholzer…·Alfred Zippelius
The paper identifies CD39+ tumor-associated NK cells as a cytotoxic effector state in NSCLC responsive to NKG2A blockade through multiomic analysis.