Markus Mukenhirn

This study shows that cancer cells adjust their nuclear volumes and proliferation rates during transitions between single and multicellular states in tumor spheroids.

This study uses programmable hydrogels to reveal two mechano-sensing timescales in MDCK cells and shows how dynamic mechanical cues influence cell polarity and morphogenesis.

This study shows that the fibrocystin C-terminal domain suppresses Src/STAT3 signaling, preventing cyst formation in kidney epithelial cells by inhibiting secretory phenotype and STAT3-dependent transcription.

The paper investigates how mechanical properties of curved epithelial tissues respond to deformation, identifying factors like viscoelasticity and cell-cell junctions that influence tissue behavior.

The paper uses single-cell RNA-Seq and imaging to study how intestinal cell types respond to viral infection, finding that each lineage has unique antiviral responses.

This study identifies Eps15 and Eps15R as key regulators of clathrin-coated plaque formation, linking ECM remodeling by focal adhesions to cell migration directionality.