Frank Hertel

Circulating immune profiling reveals impaired monocyte states and trajectories driving immunosuppression in glioblastoma

The paper identifies impaired monocyte states and trajectories in glioblastoma patients through immune profiling, revealing systemic immune reprogramming and potential therapeutic targets.

Integrative multi-omics combined with functional pharmacological profiling in patient-derived organoids identifies personalized therapeutic vulnerabilities of adult high-grade gliomas

This study integrates multi-omics and functional drug screening in patient-derived organoids to identify personalized therapeutic vulnerabilities in adult high-grade gliomas, finding distinct drug responses in IDH1 mutant and MYCN-amplified tumors.

FastField: An Open-Source Toolbox for Efficient Approximation of Deep Brain Stimulation Electric Fields

FastField provides an efficient open-source toolbox for approximating DBS electric fields and VTA, achieving high accuracy and speed compared to traditional methods.