Author

Raul Da Costa

Agency for Science, Technology and ResearchORCID 0000-0001-9666-8301Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1

Frequent Co-Authors

Oliver SoehnleiniD· 2 shared Alessandro MichelucciiD· 1 shared Alexander SkupiniD· 1 shared Almke BaderiD· 1 shared Andrea ScafidiiD· 1 shared Anna GolebiewskaiD· 1 shared Annette Zehrer· 1 shared Antonio CosmaiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Oliver SoehnleinORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Circulating immune profiling reveals impaired monocyte states and trajectories driving immunosuppression in glioblastoma

Andrea Scafidi, Tony Kaoma, Claudia Cerella, Eleonora Campus, Kamil Grzyb, Bakhtiyor Nosirov, Frida Lind‐Holm Mogensen, Eliane Klein, Raul Da Costa, Alexander Skupin, Frank Hertel, Guy Berchem, Michel Mittelbronn, Antonio Cosma, Beatrice Melin, , Alessandro Michelucci

The paper identifies impaired monocyte states and trajectories in glioblastoma patients through immune profiling, revealing systemic immune reprogramming and potential therapeutic targets.

Journal of Neuroinflammation · Jul 16, 2026Peer-reviewedCancer Biology

A Genetic Tool for Specific Tracking of Mature Neutrophils

Jiayu Cao, Hui Ping Yaw, Shilin Yi, Yanxi Zhou, Shifan Qin, Yuanyuan Wang, Raul Da Costa, Lei Zhang, Dandan Wu, Changbin Chen, Melissa Shu Feng Ng, Immanuel Kwok, Oliver Soehnlein, Xiaoxiang Chen, Jieqing Wan, Lai Guan Ng

The paper validates CD101 as a reliable marker for mature neutrophils using a reporter mouse model and shows its stability under pathological conditions.

hLife · May 28, 2026Peer-reviewedImmunology

Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis

Jincheng Gao, Almke Bader, Monika I. Linder, Jingyuan Cheng, Mathis Richter, Raul Da Costa, Annette Zehrer, Karl Mitt, Bastian Popper, Felix Meissner, Xiang Wei, Enrique de Vega Gomez, Megumi Tatematsu, Meino Rohlfs, Stephanie Frenz-Wiessner, , Daniela Begandt

This study shows that VPS18 mutations disrupt neutrophil maturation by impairing vesicle dynamics and autophagy, leading to neutropenia and recurrent infections.

Cell Death and Disease · Jan 12, 2026Peer-reviewedPhysiology