Author

Tsering Yangzom

University of BergenORCID 0000-0002-2242-722XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

Anbin CheniD· 3 shared Gareth J. SullivaniD· 3 shared Kristina Xiao LiangiD· 3 shared Bjørn Christian Lundberg· 1 shared Charalampos TzoulisiD· 1 shared Evandro Fei FangiD· 1 shared J ZemaniD· 1 shared Laurence Albert BindoffiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Anbin ChenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease

Yu Hong, Zhuoyuan Zhang, Tsering Yangzom, Anbin Chen, Bjørn Christian Lundberg, Evandro Fei Fang, Richard Siller, Gareth J. Sullivan, J Zeman, Charalampos Tzoulis, Laurence Albert Bindoff, Kristina Xiao Liang

This study uses iPSC-derived cortical organoids to model Alpers' disease and shows that nicotinamide riboside improves mitochondrial defects and neuronal loss.

International Journal of Biological Sciences · Jan 1, 2024Peer-reviewedNeuroscience

Nicotinamide Riboside Supplementation Ameliorates Mitochondrial Dysfunction and Neuronal Loss in POLG Mutant Midbrain Organoids

Tsering Yangzom, Anbin Chen, Gareth J. Sullivan, Kristina Xiao Liang

This study shows that Nicotinamide Riboside improves mitochondrial function and neuron count in POLG mutant midbrain organoids.

bioRxiv · Nov 8, 2023 · PreprintNeuroscience

Mitochondrial Dysfunction and Neuronal Anomalies in POLG Mutant Midbrain Organoids

Anbin Chen, Tsering Yangzom, Gareth J. Sullivan, Kristina Xiao Liang

This study develops a method to generate midbrain organoids from stem cells and shows that POLG mutant organoids exhibit neuronal loss and mitochondrial dysfunction, relevant to Parkinson's disease.

bioRxiv · Sep 27, 2023 · PreprintNeuroscience