Author

Yu Hong

Beijing Tongren HospitalORCID 0000-0002-3125-2855Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yu Hong1 paper · Carnegie Mellon University

Biology Disciplines

Click to filter author papers

Neuroscience· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Assay:metabolomics· 1

Frequent Co-Authors

Anbin CheniD· 2 shared Charalampos TzoulisiD· 2 shared Gareth J. SullivaniD· 2 shared Kristina Xiao LiangiD· 2 shared Laurence Albert BindoffiD· 2 shared Atefeh Kianian· 1 shared Bjørn Christian Lundberg· 1 shared Cecilie Katrin KristianseniD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Anbin ChenORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

NeuroscienceInternational Journal of Biological SciencesPeer-reviewedJan 1, 2024

The NAD+ Precursor Nicotinamide Riboside Rescues Mitochondrial Defects and Neuronal Loss in iPSC derived Cortical Organoid of Alpers' Disease

Yu Hong, Zhuoyuan Zhang, Tsering Yangzom…·Kristina Xiao Liang

This study uses iPSC-derived cortical organoids to model Alpers' disease and shows that nicotinamide riboside improves mitochondrial defects and neuronal loss.

11 citations

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintDec 20, 2020

Stem cell derived astrocytes with POLG mutations and mitochondrial dysfunction including abnormal NAD+ metabolism is toxic for neurons

Kristina Xiao Liang, Atefeh Kianian, Anbin Chen…·Laurence Albert Bindoff

This study shows that POLG mutations in astrocytes cause mitochondrial dysfunction and neurotoxicity, leading to neuronal death through altered metabolism and reactive astrocyte behavior.

4 citations

humanbulk RNA-seq

𝕏 PostBluesky