Author

Eric P. Schultz

University of MontanaORCID 0000-0002-2259-6912Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

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Brent J. RyckmaniD· 1 shared Florian KleiniD· 1 shared Jean-Marc Lanchy· 1 shared Lars Ponsness· 1 shared Matthias ZehneriD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperMicrobiology

Brent J. RyckmanORCID

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1 paper

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedApr 9, 2025

Human cytomegalovirus gH/gL/gO binding to PDGFRα provides a regulatory signal activating the fusion protein gB that can be blocked by neutralizing antibodies.

Eric P. Schultz, Lars Ponsness, Jean-Marc Lanchy…·Brent J. Ryckman

This paper develops a cell-cell fusion assay to study HCMV gH/gL/gO receptor engagement and its role in activating gB fusion, showing that PDGFR binding enhances fusion and can be blocked by neutralizing antibodies.

7 citationstop 5%

humanexperimental assay

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