ImmunologybioRxivPreprint
SELECTION OF ANTI-NUCLEAR ANTIGEN (ANA) REACTIVE B CELLS IN SYSTEMIC LUPUS ERYTHEMATOSUS.
Yemil Atisha‐Fregoso, Wenzhao Meng, Aaron M. Rosenfeld…·Betty Diamond
This study analyzes B cell receptor sequences in SLE patients to understand autoreactive B cell selection and differentiation, finding that ABCs are enriched in autoreactivity and may arise from naive B cells through an extrafollicular pathway.
DOI 10.1101/2025.01.08.631945