Author

Eline T. Luning Prak

University of PennsylvaniaORCID 0000-0002-9478-9211Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Ali NajiiD· 2 shared Gregory J. GoldeniD· 2 shared Klaus H. KaestneriD· 2 shared Mark A. AtkinsoniD· 2 shared Michael R. BettsiD· 2 shared Todd M. BruskoiD· 2 shared Aaron M. RosenfeldiD· 1 shared Alberto Sada JappiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

Ali NajiORCID

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3 papers

Recent·Most cited

Spatial transcriptomics from pancreas and local draining lymph node tissue reveals a lymphotoxin-β signature in human type 1 diabetes

Miguel A. Medina-Serpas, Maigan Brusko, Gregory J. Golden, Martha Campbell‐Thompson, Trevor Rogers, Shay Reardon, Amanda L. Posgai, Rhonda L. Bacher, Eline T. Luning Prak, C Liu, Klaus H. Kaestner, Ali Naji, Michael R. Betts, Lauren M. McIntyre, Mark A. Atkinson, Todd M. Brusko

This study uses spatial transcriptomics to identify inflammation signatures in pancreas and lymph node tissues of T1D patients, highlighting LTB and other genes involved in disease pathogenesis.

Cell Reports · Mar 23, 2026Peer-reviewedImmunology

Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset

Gregory J. Golden, Vincent H. Wu, Jacob T. Hamilton, Kevin R. Amses, Melanie R. Shapiro, Alberto Sada Japp, Chengyang Liu, María Betina Pampena, Leticia Kuri-Cervantes, James J. Knox, Jay S. Gardner, Mark A. Atkinson, Todd M. Brusko, Eline T. Luning Prak, Klaus H. Kaestner, , Michael R. Betts

The paper analyzes immune cell changes in human pancreas-draining lymphatic tissues before and after T1D onset, identifying proinflammatory patterns and genetic risk correlations.

Nature Communications · May 18, 2025Peer-reviewedImmunology

SELECTION OF ANTI-NUCLEAR ANTIGEN (ANA) REACTIVE B CELLS IN SYSTEMIC LUPUS ERYTHEMATOSUS.

Yemil Atisha‐Fregoso, Wenzhao Meng, Aaron M. Rosenfeld, Fang Liu, Thomas MacCarthy, Scott M. Feltman, Cynthia B. Aranow, Meggan C. Mackay, Chloe Terestchenko, Moriah Dunn, Matthew D. Scharff, Eline T. Luning Prak, Betty Diamond

This study analyzes B cell receptor sequences in SLE patients to understand autoreactive B cell selection and differentiation, finding that ABCs are enriched in autoreactivity and may arise from naive B cells through an extrafollicular pathway.

bioRxiv · Jan 8, 2025 · PreprintImmunology