Author
Institute of Structural and Molecular BiologyORCID 0000-0002-2266-8891Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Z.P. Wang, Samantha L. Weetman, Barbara Altenhuber…·Wenjuan Zhang
This study shows that chaperones shape the structural evolution of yeast prion amyloids during maturation, with Hsp104 inhibiting structural diversity.
Guendalina Marini, Brad Poland, Chris Leininger…·Helen R. Saibil
The paper reveals the molecular mechanism of an insecticidal protein through 3D structures of its three main pore formation states.
Ya Zhou, Thomas R. Peskett, Christian Landles…·Helen R. Saibil
This study uses correlative light and electron microscopy to show that mutant huntingtin accumulates in endolysosomal organelles in presymptomatic Huntington's disease, altering endolysosomal homeostasis.