Stephanie R. Shames

This paper identifies BinA, a Legionella effector that rewires amino acid transport to sensitize mTORC1 signaling in macrophages, enhancing bacterial replication.

This study determines the crystal structure of Legionella pneumophila effector SidL complexed with its metaeffector LegA11, showing how LegA11 suppresses SidL's mRNA translation inhibition activity.

This study develops a neonatal mouse model to investigate gut colonization by carbapenem-resistant Enterobacter hormaechei, revealing mucus metabolism as a key factor in intestinal colonization.

This study shows that the Legionella effector LegC4 enhances cytokine-mediated restriction of Legionella replication in macrophages.