Victor J. DiRita

This study shows that microbiota-derived indole inhibits Campylobacter jejuni colonization by disrupting its respiration and metabolism in an inflamed gut.

This study develops a neonatal mouse model to investigate gut colonization by carbapenem-resistant Enterobacter hormaechei, revealing mucus metabolism as a key factor in intestinal colonization.

The paper identifies 18 conserved fitness genes in Enterobacterales species that contribute to bacteremia pathogenesis by testing mutants in a mouse model and finding attenuation in multiple organs.

The paper integrates Tn-Seq fitness data with functional data to identify seven common fitness mechanisms across five Enterobacterales species, validating one gene's role in bacteremia and antibiotic resistance.