Author

Jinyue Pu

University of ChicagoORCID 0000-0002-2314-7190Unclaimed ORCID profile · follow to get notified of new preprints

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:protein structure· 1

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Bryan C. DickinsoniD· 1 shared Cristina LentoiD· 1 shared Derek J. WilsoniD· 1 shared Esther WolfiD· 1 shared

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2023-2023 · peak 1/yr

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1 shared paperMolecular Biology

Bryan C. DickinsonORCID

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1 paper

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Molecular BiologyBiochemistryPeer-reviewedMay 16, 2023

Innate Conformational Dynamics Drive Binding Specificity in Anti-Apoptotic Proteins Mcl-1 and Bcl-2

Esther Wolf, Cristina Lento, Jinyue Pu…·Derek J. Wilson

This study uses hydrogen deuterium exchange mass spectrometry to show that Mcl-1's binding specificity arises from dynamic modes in its unbound state, distinct from Bcl-2.

8 citations

protein structureexperimental assay

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