Expery O. Omollo

The paper identifies a new feature of bacterial intrinsic transcription terminators, showing that dinucleotides at the edges of the transcription bubble are critical for termination efficiency.

The paper reports cryo-EM structures of E. coli intrinsic termination complexes to define the structural mechanism of bacterial transcription termination.

This study identifies MtbNusG as a pro-pausing transcription factor that stabilizes paused RNAP through specific structural interactions, with implications for NusG function across domains of life.