PhysiologybioRxivPreprint
Nutrient-Sensing Nuclear Receptor PPARα Controls Liver Proteostasis
Jinse Kim, Noor Bains, Kaylin G. Maddox…·David D. Moore
This study identifies PPARα as a regulator of liver proteostasis, showing it suppresses protein synthesis and secretion while enhancing proteasome activity and degradation.
DOI 10.1101/2025.09.01.673563