Taylor M. Nichols

This study investigates the role of signal sequences in bacterial microcompartment (MCP) assembly, showing that structural protein signal sequences are critical for MCP formation and that their deletion causes defects similar to full gene knockout.

The paper shows that different imaging techniques produce varying apparent sizes and morphologies of bacterial microcompartments from Salmonella enterica serovar Typhimurium LT2, and provides guidelines for sample preparation.