Joshua Mayourian

This study shows that RBFOX2 autoregulation is critical for cardiomyocyte differentiation by maturing the transcriptome, and its disruption leads to congenital heart disease.

This paper introduces REVi-SCOPE, a platform that rapidly characterizes cardiac variants' functional impact, enabling precision cardiology by analyzing VUSs in 10 days.

This study applies CASAAV-HDR to model cardiomyopathies and perform functional genomics in mouse cardiomyocytes, showing its utility for disease modeling and enhancer analysis.

This paper describes a method to generate high-purity, scalable human iPSC-derived cardiomyocytes using a bioreactor, showing improved viability, function, and consistency compared to traditional methods.