Guangjin Pan

The paper shows that embryonic stem cells use asymmetric division in a two-cell-like state to rejuvenate and maintain lineage immortality by segregating DNA damage.

This study shows that a CTCF R567W mutation causes developmental disorders by altering 3D genome structure and neurodevelopmental pathways in mouse and human models.

Single cell RNA sequencing identifies two reprogramming branches in mouse fibroblasts, with Dppa5a marking pluripotent cells and IFN-gamma inhibiting the transition.