Thomas Le Saux

The paper introduces non-covalent reversibly photoconvertible fluorescent proteins that change color under illumination, enabling discrimination of spectrally similar variants in live cells.

This paper introduces RSpFAST, a non-covalent chemogenetic platform for fluorescence imaging, and demonstrates its dual behavior as a stable label and a reversible photoswitcher.

This study uses single-cell analysis to reveal cell-to-cell heterogeneity and a correlation between high-energy quenching and state transitions in Chlamydomonas reinhardtii under light stress.

The paper engineers a fluorescent chemogenetic reporter with tunable color for live-cell imaging, enabling advanced spectral control and compatibility with advanced imaging techniques.