Author

Yuriy Shpinov

Centre National de la Recherche ScientifiqueORCID 0009-0004-4298-1465Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:protein folding & dynamics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:imputation· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Arnaud GautieriD· 3 shared Lina El HajjiiD· 3 shared Ludovic JullieniD· 3 shared Aliénor LahlouiD· 2 shared Franck PereziD· 2 shared Ian CoghilliD· 2 shared Isabelle Aujard· 2 shared Marie‐Aude PlamontiD· 2 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersBiophysics

Arnaud GautierORCID

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3 papers

Recent·Most cited

BiophysicsAdvanced SciencePeer-reviewedSep 29, 2026

Non-covalent reversibly photoconvertible fluorescent tags for wash-free protein labeling

Mrinal Mandal, Yuriy Shpinov, Aliénor Lahlou…·Ludovic Jullien

The paper introduces non-covalent reversibly photoconvertible fluorescent proteins that change color under illumination, enabling discrimination of spectrally similar variants in live cells.

DOI 10.1002/advs.78041

fluorescence / live-cell microscopyexperimental assay

𝕏 PostBluesky

BiochemistryJournal of the American Chemical SocietyPeer-reviewedAug 25, 2026

Kinetic and Mechanistic Characterization of RSpFAST, A Non-Covalent Versatile Chemogenetic Platform for Fluorescence Imaging

Yuriy Shpinov, Mrinal Mandal, Vincent M.L. Van Deuren…·Ludovic Jullien

This paper introduces RSpFAST, a non-covalent chemogenetic platform for fluorescence imaging, and demonstrates its dual behavior as a stable label and a reversible photoswitcher.

DOI 10.1021/jacs.6c08277

fluorescence / live-cell microscopyexperimental assay

𝕏 PostBluesky

Cell BiologyACS SensorsPeer-reviewedApr 6, 2026

Chemogenetic modulation of luciferase emission color for imaging and sensing

Horgan Manirakiza, Yuriy Shpinov, Amandine Gontier…·Arnaud Gautier

This paper introduces LumiFAST, a tunable luciferase that enables customizable red-shifted emission for improved imaging and biosensing in live cells.

DOI 10.1021/acssensors.5c04421

proteomicsexperimental assay

𝕏 PostBluesky