Author

Yi Wee Lim

Agency for Science, Technology and ResearchORCID 0000-0002-2387-9332Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:CRISPR screen· 1 Organism:E. coli· 1

Frequent Co-Authors

Elena Heng· 3 shared Fong Tian WongiD· 3 shared Yee Hwee LimiD· 3 shared Cyrus Weijie BehiD· 1 shared Dillon W. P. TayiD· 1 shared Elaine TiongiD· 1 shared Guangrong Peh· 1 shared Huimin ZhaoiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersSynthetic Biology

Elena Heng

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Accelerating Natural Product Discovery with Linked MS-Genomics and Language/Transformer-Based Models

Dillon W. P. Tay, Winston Lian Chye Koh, Shi Jun Ang, Zicong Marvin Wong, Yi Wee Lim, Elena Heng, Yu Hung Ng, Naythan Z. X. Yeo, Krishnan Adaikkappan, Fong Tian Wong, Yee Hwee Lim

The paper integrates mass spectrometry and genomics data with language models to accelerate natural product discovery in microbial strains.

npj Antimicrobials and Resistance · Apr 30, 2026Peer-reviewedSynthetic Biology

Hyperporous encapsulation of microbes for whole cell biocatalysis and biomanufacturing

Jingyi Zhang, Keziah Chang, Joyce Tay, Elaine Tiong, Elena Heng, Theresa Seah, Yi Wee Lim, Guangrong Peh, Yee Hwee Lim, Fong Tian Wong, Cyrus Weijie Beh

This paper develops a hyper-porous hydrogel encapsulation method for microbial cells, demonstrating improved biocatalytic efficiency in co-culture fermentation.

Microbial Cell Factories · Feb 24, 2025Peer-reviewedBioengineering

Characterization of Cas proteins for CRISPR-Cas editing in streptomycetes

Wan Lin Yeo, Elena Heng, Lee Ling Tan, Yi Wee Lim, Yee Hwee Lim, Shawn S. Hoon, Huimin Zhao, Mingzi M. Zhang, Fong Tian Wong

The paper evaluates alternative CRISPR-Cas systems for genome editing in streptomycetes, showing that sth1Cas9, saCas9, and fnCpf1 enable efficient genomic modifications where SpCas9 fails.

Biotechnology and Bioengineering · May 15, 2019Peer-reviewedSynthetic Biology